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Department of Chemical & Biological Sciences

Head of Department

Dr. Amit Kumar Paul
Ph.D, IACS, University of Calcutta

E-mail:
hod.cy@nitm.ac.in

Ph.D

Mr. Sharat Sarmah Research Scholar

  • B. Sc. Chemistry from DKD College, Dibrugarh University (2015)
  • M. Sc. Chemistry from NIT Meghalaya (2017).

sharatsarmah@nitm.ac.in sharatsarmah92@gmail.com
+918876172941
Full Time/Part Time Scholar: Full-Time

Highest Degree with specialization(Name of Institute):

  • M.Sc Chemistry (NIT Meghalaya)

Research Area:

  • Study of protein-Ligand Interaction using biophysical techniques.
  • Glycation, fibrillation induced structural and functional changes in proteins.
  • Inhibition and mechanism associated with the inhibition of glycation and fibrillation.
  • Interaction of Cu(II) complexes of natural compounds with proteins and DNA.
  • DNA damaging, antibacterial and anticancer activities of Cu(II) complexes.

Seminar/Conference Attended:

  • Workshop on Biophotonics - A Multidisciplinary Approach, November 18-19th, NIT Meghalaya, 2016
  • National Workshop on Fluorescence And Raman Spectroscopy, FCS-2018, November 12-19, JNU, Delhi.
  • International conference on “Advances in chemical science and technology, ACST-2019, September 23-25, NIT Warangal, Telangana.
  • National Conference on Recent Advances in Chemistry, RAC-2019, October 14-15, NIT Meghalaya, Shillong. Research Conclave, NIT Meghalaya, 2020
  • Innovations in Chemical Sciences-2020 Organized by Division of Chemistry, VIT Chennai, Chennai.
  • Webinar on "Basics of Gas Adsorption: Physisorption Technique, 29th January 2021
  • International Seminar on Recent Advances in Chemistry & Material Sciences (2020) organized by the Indian Chemical Society to commemorate the 159th Birth Anniversary of Acharya Prafulla Chandra Ray.
  • Research Conclave, NIT Meghalaya, 2021
  • International conference on recent developments in chemistry, RDC 2021, March 3-5th, NIT Durgapur

Research Publications/Book Chapters:

  • Singha Roy, A., Sarmah, S, Das, S., Effects of Glycation on Serum albumin, in A Closer Look at Glycation, Nova Science publishers, 2021, pp 21-78. ISBN: 978-1-53619-176-9.
  • S. Sarmah, S. Das, A. Singha Roy*, Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum albumin: iIn vitro and molecular docking analysis, International Journal of Biological Macromolecules, 165, 2020, 2275-2285. DOI: doi.org/10.1016/j.ijbiomac.2020.10.023.
  • S. Sarmah, S. Pahari, V. K. Belwal, M. Jana*, A. Singha Roy*, Elucidation of molecular interaction of bioactive flavonoid luteolin with human serum albumin and its glycated analogue using multi-spectroscopic and computational studies, Journal of Molecular Liquids, 2020, DOI: https://doi.org/10.1016/j.molliq.2020.114147.
  • S Das, S Sarmah, S Lyndem, A Singha Roy, An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study, Journal of Biomolecular Structure and Dynamics, 2020, DOI: doi.org/10.1080/07391102.2020.1763201.
  • S. Rana, S. Sarmah, A. Singha Roy, K. S. Ghosh*, Elucidation of molecular interactions between human ?D-crystallin and quercetin, an inhibitor against tryptophan oxidation, Journal of Biomolecular Structure and Dynamics, 2020, DOI: 10.1080/07391102.2020.1738960.
  • S. Das, Z. Hazarika, S. Sarmah, K. Baruah, M. A. Rohman, D. Paul, A. N. Jha, A. Singha Roy*, Exploring the interaction of bioactive kaempferol with serum albumin, lysozyme and hemoglobin: A biophysical investigation using multi-spectroscopic, docking and molecular dynamics simulation studies, Journal of Photochemistry and Photobiology B: Biology, 2020, DOI: 10.1016/j.jphotobiol.2020.111825.
  • S. Sarmah, S. Pahari, S. Das, V. K. Belwal, M. Jana*, A. Singha Roy*, Non-enzymatic glycation of human serum albumin modulates its binding efficacy towards bioactive flavonoid chrysin: A detailed study using multi-spectroscopic and computational methods, Journal of Biomolecular Structure and Dynamics, 2020, DOI: 10.1080/07391102.2019.1711196.
  • S. Das, S. Sarmah, Z. Hazarika, M. A. Rohman, P. Sarkhel, A. N. Jha, A. Singha Roy*, Targeting the heme protein hemoglobin by (-)-epigallocatechin gallate and the study of polyphenol-protein association using multi-spectroscopic and computational methods, Physical Chemistry Chemical Physics, 2020, DOI: 10.1039/C9CP05301H.
  • S. Das, S. Sarmah, A. Singha Roy*, Monitoring Fluorescence Emission Behaviors of Dietary Polyphenols in Serum Albumin Environment, New Journal of Chemistry, 2019, DOI: 10.1039/C9NJ03938D.
  • S. Das, S. Pahari, S. Sarmah, M .A. Rohman, D. Paul, M. Jana*, A. Singha Roy*, Lysozyme-luteolin binding: Molecular insights into the complexation process and the inhibitory effects of luteolin towards protein modification, Physical Chemistry Chemical Physics, 2019, 21, 12649-12666. DOI: 10.1039/C9CP01128E.

Any other remarkable Experience:

  • Summer internship on “An investigation into the binding of dietary polyphenols with bovine serum albumin : A molecular docking study”, June-July, NIT Meghalaya, 2016.
  • 2018-2020: Physical Chemistry laboratory classes as TA duty.
  • 2019-2020: B.Tech Chemistry laboratory classes as TA duty.
  • Spring 2020: Analytical Chemistry laboratory as TA duty.